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The carbon from serine (specifically carbon 3) represents the major source of the one carbon (1C) units transferred during reactions utilizing THF
There is limited direct evidence for this specific stack in controlled studies, and clinicians considering it should weigh the additive mechanistic logic against the absence of human safety data for the combination
Each serves a distinct research question
If youre combining B12 with a MIC Lipotropic shot (B vitamins plus amino acids for fat metabolism), youll typically only need a weekly B12 injection thereafter
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