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Clinical evidence suggests an association between GLP-1 receptor agonists and dual GIP/GLP-1 receptor agonists with increased risk of gallbladder-related complications, though the relationship is complex and not fully characterized

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ELISA The inflammatory cytokines in the supernatants of FLS or the serum of rats were detected with ELISA kits as described by the manufacturer

Furthermore, broad-spectrum depalmitoylase inhibitors such as Palmostatin B/M, which covalently target both APT1 and APT2 [178], were initially characterized for their ability to disrupt the S-palmitoylation cycle of oncogenic Ras [179, 180]