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Description

Large trials have consistently shown that statins reduce the risk of major cardiovascular events by around 25-35% in people at elevated risk, and this benefit holds regardless of starting cholesterol level

The mechanism is well-characterized at the biochemical level: GSH inhibits tyrosinase, the rate-limiting enzyme in melanin biosynthesis, by binding to its copper-containing active site

Injectable semaglutide and dulaglutide have demonstrated robust A1C reductions along with well-established cardiovascular benefits