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Studies show improved outcomes in models of osteoarthritis and joint damage, likely mediated through growth factor upregulation and anti-inflammatory pathways
However, in plant kingdom, only an amino acid and a protein, namely the glutamate (Glu) and the recently discovered Riccas factor -THIOGLUCOSIDE GLUCOHYDROLASE (TGG) are so far defined as wound signals that depend on glutamate receptor-like (GLR) protein, the homologous protein of mammalian ionotropic Glu receptors (iGluRs), to activate systemic plant defense response 6,7,11
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