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while significant pharmacokinetic interactions with psychiatric medications are not generally expected, GLP-1 agonists may affect absorption of some oral medications due to delayed gastric emptying Discuss realistic expectations regarding weight loss and diabetes control to avoid disappointment that might affect mood Ensure adequate support systems are in place, including regular contact with healthcare providers Discuss pregnancy plans as these medications are not recommended during pregnancy or breastfeeding
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although multivariable analyses were performed, residual confounding from unmeasured variables cannot be excluded
Functional MTP is composed of a large catalytic -subunit encoded by the MTTP gene and a small -subunit which is a member of the protein disulfide isomerase (PDI) family of proteins that are involved in the processes of protein folding in the ER
