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Cell death and diseases related to oxidative stress: 4-hydroxynonenal (HNE) in the balance
In severe acute pancreatitis (SAP), inflammatory factors promote the expression of matrix metalloproteinases (MMPs) and heparinases, which degrade syndecan-1 (SDC-1) and HS, while oxidative stress disrupts HA-CD44 binding, leading to increased capillary leakage and neutrophil adhesion
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Eur J Inflamm 21:1721727X231154152 Merz KE, Thurmond DC (2020) Role of Skeletal Muscle in Insulin Resistance and Glucose Uptake
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