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They possess a high synthetic capacity for GSH due to high expression of (GCL) and cystine/glutamate antiporter (xCT), and can export GSH to neighboring neurons and glia

This phase of the pathway consists of several important steps that include: Step 1 - In this step of the oxidative phase, the enzyme glucose 6-phosphate dehydrogenase, in the presence of NADP+ (a universal electron acceptor), converts glucose 6-phosphate into 6 phosphoglucono delta lactone

10.1093/humrep/deab190 53 Romero-ReyesJ.CrdenasM.Damin-MatsumuraP.DomnguezR.AyalaM

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