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They should mainly be used as second-line therapy as add on to metformin in patients with type 2 diabetes who have no pre-existing cardiovascular disease and have a therapeutic goal to avoid hypoglycaemic events
By activating these receptors, Tirzepatide enhances insulin secretion, inhibits glucagon release, slows gastric emptying, and reduces food intake, leading to improved glycemic control and weight reduction
Like all medications, weight loss injectables are used alongside proper nutrition and daily activity, not as a substitute for them
Aging, atherosclerosis, and IGF-1 [PMID: 22491965] Laboratory literature summary: Aging, atherosclerosis, and IGF-1
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