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Here we investigate the effects of liraglutide, a GLP-1 receptor agonist, in two well characterised transgenic mouse models of ALS (SOD1 G93A and TDP-43 Q331K ) to determine if liraglutide could be a potential treatment in ALS patients

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Given the distinct modes of action exhibited by these peptides, their concomitant exposure may potentially augment growth hormone response in a synergistic manner