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In human clinical use, reported side effects are generally mild and transient: Mild injection site redness or discomfort (resolves within hours) Transient nausea in some patients, particularly early in the protocol Mild dizziness or light-headedness (rare, typically dose-related) Temporary fatigue in the first few days (often a sign of active tissue remodeling) No significant systemic toxicity, organ damage, hormonal suppression, or addiction potential has been documented in the published literature
Lung histopathology indicated that ACA given at 50 mg/kg/day could reverse the OVA-induced alterations such as eosinophil infiltration, mucus plugs, goblet-cell hyperplasia, and airway remodeling
Intermediate Protocol After establishing tolerance, add weekly microneedling with a 0.25-0.5mm dermaroller
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