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MiR-25 is overexpressed in both keratinocytes and melanocytes in response to oxidative stress, which decreases the activity of antioxidant enzymes and impairs melanosome transport, leading to redox imbalance [51]

Differentially expressed genes in GSTP1 knockdown cells were identified by Illumina HT-12 expression arrays and qRTPCR analysis, and altered pathways predicted by MetaCore (GeneGo) analysis

It acts as a master regulator, boosting genes involved in cellular repair, reducing inflammation, and promoting tissue regeneration, while down-regulating genes that trigger unwanted inflammatory responses

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