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Providers see this kind of adjustment regularly across metabolic treatment plans, and it reflects routine clinical judgment rather than a rigid rule
siGAPDH) = 0.1624)
Specifically, the IGF-1-PI3K-Akt-mTOR cascade promotes protein synthesis and suppresses protein degradation by phosphorylating downstream FoxO, thereby inhibiting E3 ligases (MuRF1 and atrogin-1) (73,81)
