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GLP-1 medications include injectable forms such as semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), and liraglutide (Victoza, Saxenda), as well as oral semaglutide (Rybelsus)
The PV1-SC7 sVLP harbors seven stabilizing amino acid substitutions, such as VP1 V196L, VP1 H248P, and VP3 Q178L, which enhance PV1 EC stabilization
These medications slow gastric emptying and reduce appetite, which can inadvertently decrease fluid intake while increasing the risk of dehydration through gastrointestinal symptoms like nausea, vomiting, and diarrhea
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