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In clinical contexts, AOD 9604 has also been evaluated in obesity-related trials, where ongoing work continues to assess its potential role
J Mol Endocrinol
Available reports describe 5-Amino-1MQ as selective for NNMT within tested experimental panels, but those panels do not equal a complete off-target safety profile across all methyltransferases, non-methyltransferase proteins, cell types, exposure durations, or intracellular conditions
Cyanocobalamin is contraindicated in these individuals as the cyanide moiety may worsen optic nerve damage
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