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Tirzepatide acts on two receptors (GLP-1 and GIP), while semaglutide acts on one (GLP-1)
For example, a 5 mg vial at 1 mg/mL needs 5 mL
In trials where semaglutide was added on to basal insulin with or without metformin, severe hypoglycemia (requiring the assistance of another person) was reported in 1.5% of semaglutide-treated patients
Ask about outcomes data and whether a peptide is FDA-approved. Anecdotes, he says, are not enough
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