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His average systolic blood pressure improved from ~170 to ~140 despite discontinuation of his antihypertensive regimen, and his chronic non-healing leg wound resolved without antibiotics
People with type 1 diabetes need to be especially cautious with GLP-1 medications because of DKA
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Compelling evidence from landmark clinical trials, particularly STEP-HFpEF, STEP-HFpEF DM and SUMMIT, has established the efficacy of GLP-1RAs in improving HF-related symptoms and quality of life, as well as reducing worsening HF events, in the prevalent phenotype of HFpEF in the setting of obesity and T2D
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