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If it's past that, it's a clear sign
Gastrointestinal discomfort, changes in eating patterns, and metabolic shifts can all interfere with sleep quality
The results of a trial of semaglutide in obese patients with HFpEF showed a significant amelioration of symptoms and improvements in motor function and weight loss compared with patients treated with a placebo.470 In this study, researchers randomized 529 patients with heart failure with a preserved ejection fraction and body mass index (weight in kilograms in the square of the height in meters) 30 to receive once-weekly injections of semaglutide (2.4 mg) or placebo for 52 weeks
J Mol Endocrinol (1993) 10(3):25968
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