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On this basis, the presence of microvascular alterations in a pre-diabetic mouse model also suggests that early hyperinsulinaemia and insulin resistance are sufficient to induce vascular damage and that bloodbrain barrier dysfunction precedes cognitive decline (25)
In laboratory research, the peptide is investigated for its role in signaling pathways associated with nitric oxide regulation, angiogenic signaling cascades, and cellular stress responses
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Brcic, M
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