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In patients with severe intellectual and motor disabilities, Murata and collaborators reported that the level of free carnitine was significantly correlated with gastric emptying and the severity of constipation and this level was significantly lower in the patients who suffered from constipation
Well-known drugs like semaglutide (Ozempic and Wegovy ) act on this pathway
So we need to do the work and partner with people in the community with social capital so we can connect with people and reduce harm that way. Harm reduction services Hughes says the NZ Drug Foundation is also working to target different groups who have typically never engaged with needle exchange services
These actions combined help decrease the patients caloric intake and allow them to feel satiety after consuming smaller portion sizes
