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The recommended starting dosage is 0.5 mg/m 2 /day in children and 0.10.2 mg/day in adults by monitoring the IGF-I values, which should be maintained within the upper half of the reference range [13]

Tumor volume was significantly decreased in mice given 150 mg/kg T3E orally once every 2 days for 10 days without any reduction in body weight, indicating that T3E might have anti-MM effects (122)

Numerous clinical trials have investigated the effects of silexan in individuals with anxiety disorders, subclinical anxiety, and anxiety-related symptoms such as difficulty sleeping