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Additional factors that increase the risk of SLE are anti-nuclear antibody positivity, periungual involvement, joint pain, anaemia, and low white blood cell counts
The most robust evidence to date comes from the phase 2 randomised controlled trial (Jastreboff et al., NEJM , 2023)
Beta-blockers can exacerbate these conditions and impair their ability to be properly managed with standard treatment protocols
Yes, and many patients do
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