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For example, people may not experience the physical reminder to eat consistently and regularly throughout the day and instead must consciously remind themselves, which can exacerbate a poor relationship with food

[57] In individuals with obesity, chronic low-grade inflammation often leads to "leptin resistance"a pathological state where circulating leptin levels are high, but the brain fails to register the signal, leading to persistent hunger

Obesity is a chronic disease exacerbated by a complex array of biological, social, environmental, and structural forces