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Discontinuation rates owing to adverse events were 4.1%, 6.9%, 11.3%, with retatrutide 4mg, 9mg, and 12mg, respectively, compared with 4.9% with placebo, the study results revealed

Data shows that after stopping GLP-1 injectables, people experience 60-70% weight regain within one year and full weight regain after three to four years without intervention

Semaglutide may support appetite regulation, but insulin resistance may still need to be addressed as part of a broader medical plan