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GLP-1 medications arent suitable for pregnant or breastfeeding women, those with certain thyroid conditions, pancreatitis history, or severe gastrointestinal issues

This is why brand-name products can confidently assign 24-month or longer expiration dates

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Key challenges include: Low Bioavailability : Flavonoids often have low bioavailability in humans due to poor absorption and rapid metabolism, which limits the active concentration of flavonoids in systemic circulation and reduces their effectiveness in miRNA modulation (Thilakarathna and Rupasinghe, 2013)