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Lilly USA LLC is the only United States company with FDA-approved products containing tirzepatide identified under the trade names Zepbound and Mounjaro Results based on a January 2026 analysis of 14,203 Noom GLP-1Rx Program members who actively logged weight over a 40-week period
Most are mild and include nausea, vomiting, and diarrhea
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While semaglutide itself is not majorly metabolized by CYP3A4, the risk comes from compounding effects when grapefruit is combined with other medications you may take simultaneously, such as blood pressure drugs, cholesterol medications, or antihistamines
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