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Its important to throw away your pen if it has been: frozen exposed to light exposed to temperature above 86F (30C) out of the refrigerator for longer than 28 days Wegovy storage after opening After opening Wegovy, you can store your pens in their original cartons in the refrigerator at a temperature of 36F to 46F (2C to 8C)

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In addition to their effects on appetite, GLP-1 agonists also slow down gastric emptying, which can further contribute to weight loss