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Compared to exogenous recombinant GH (somatropin), Tesamorelin preserves the physiological pulsatility of endogenous secretion, maintaining better tissue response, avoiding GH-R desensitization, and presenting a more balanced metabolic profile (glycemic neutrality vs diabetogenic effect often documented with high-dose exogenous GH)
Tesamorelin holds no UK marketing authorisation and would require importation as an unlicensed medicine on a named-patient basis, with full clinical and legal responsibility resting with the prescribing clinician
ALCAR) is an orally active mitochondrial energy metabolism regulator and neuroprotectant that can penetrate the blood-brain barrier
The erratic nerve signaling that causes the rapid heart rate and blood pressure swings in POTS is worsened by the lack of antioxidant protection in the central nervous system
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