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Reynolds et al., 2021)
Results Median BAC decreased from baseline 123 g/dl to 95.5, 88, 83, 96, and 86 g/dl at 12, 24, 48, 96, and 192 weeks, respectively (all P 1500 mg/day) achieve more rapid BAC normalization and should be considered for patients with significant hyperammonemia
Spann NJ, Garmire LX, McDonald JG, Myers DS, Milne SB, Shibata N, Reichart D, Fox JN, Shaked I, Heudobler D, Raetz CR, Wang EW, Kelly SL, Sullards MC, Murphy RC, Merrill AH Jr., Brown HA, Dennis EA, Li AC, Ley K, Tsimikas S, Fahy E, Subramaniam S, Quehenberger O, Russell DW, Glass CK (2012) Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses
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