Bianchi A, De Castro Silva I, Deshpande NU, Singh S, Mehra S, Garrido VT, et al
Type of study: non-rct in vitro Number of citations: 15 Year: 2023 Authors: Ying-Yin Zhu, Wuqing Xiao, Wanling Zhong, Chen Xi, Jinhong Ye, Qing Zhang, Huichao Wu, Shouying Du Journal: International journal of pharmaceutics Journal ranking: Q1 Key takeaways: The combined system of Cur-Lips and skin-penetrating peptide TD-1 effectively promotes skin penetration and has great potential for melanoma prevention and treatment
Therefore, we performed pharmacokinetic studies of BPC157 in rats following a single intravenous (IV) administration of 20 g/kg, single intramuscular (IM) administration of doses 20, 100, or 500 g/kg, and repeated IM administrations of 100 g/kg of BPC157 for seven consecutive days
The formula addresses this from four angles simultaneously: providing BPC-157 to support the GI environment, feeding butyrate-producing microbes with MicrobiomeX prebiotic, supplying a butyrate-producing bacterial strain directly (Clostridium butyricum), and delivering preformed butyrate to the colon via ButyroGen tributyrin