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GLP-1RAs can inhibit the growth of cervical cancer and breast cancer induced by high glucose by inhibiting the expression of PSMA2 and phosphorylated p65 and IB
Germany Focuses on Private Sector Treatment Access Demand for obesity GLP-1 treatment in Germany is projected to grow at a CAGR of 19.6%, constrained by statutory health insurance exclusions for anti-obesity medications that limit public reimbursement
Storage: Reconstituted peptide solutions should generally be stored in a refrigerator at 28C and protected from light Avoid freezing the reconstituted solution In-use shelf life must follow product-specific validated stability data
Supplementary Table 5 (download XLSX Investigated_Drug_MoA (Names of all MoA classes with more than five drugs, area under the curve values from ROC curve analysis, number of drugs in the MoA Class, drug names) / t-test_p-values ( P values per metabolite and MoA class from t -test comparing drugs of an MoA class to all other drugs) / mean_zscores_metabolites (mean z-score per metabolite across all drug perturbations of an MoA class) / PEA_p-values ( P values per metabolic pathway (KEGG) and MoA class from pathway enrichment analysis (PEA) using all drugs from an MoA) / PEA_q-values ( q values per metabolic pathway (KEGG) and MoA class from PEA using all drugs from an MoA) / mean_ zscores_pathways (mean z-score per metabolite pathway across all drug perturbations of an MoA class) / median_zscores_pathways (median z-score per metabolite pathway across all drug perturbations of an MoA class)
