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Used in in vitro research examining combined pharmacodynamics of GHRH receptor and GHSR-1a co-activation, cooperative cAMP accumulation assays, and receptor cross-talk studies in cell line models co-expressing both receptors
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Human embryonic kidney (HEK) 293T cells recombinantly expressing human GIPR or cynomolgus monkey GIPR and Chinese hamster ovary (CHO) cells expressing rat or mouse GIPR were used to measure cyclic adenosine monophosphate (cAMP) accumulation
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