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Physical Therapy: Physical therapy offers a non-addictive approach to managing pain by improving mobility, strengthening muscles, and reducing reliance on medications
The mechanistic plausibility is strong (NNMT inhibition increases NAD+ without the gastrointestinal side effects of high-dose nicotinamide), and the short-term tolerability profile is excellent, but we mean this sincerely: if you're using this compound for durations beyond what the published trials covered, you are operating in uncharted territory
Other side effects to be aware of include insomnia on tirzepatide , sleep disruption on semaglutide , dizziness on semaglutide , and body aches on tirzepatide
You may notice increased difficulty with physical activities that were previously manageable, or a general sense of exhaustion that affects daily functioning
