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By inhibiting DPP-4, sitagliptin increases the concentration of two known active hormones of the incretin family: glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)

Nutritional studies in model organisms and rodents have revealed potential links to longevity and distinct mechanistic factors, lending credence to the association between diet and longevity [65]

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Clinical trials show that medications like Wegovy (semaglutide) and Zepbound (tirzepatide) not only help shed pounds but also improve overall health markers including blood pressure and cholesterol levels