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Serious side effects can include severe hypoglycemia and allergic reactions
Lipophilic drugs may also be inadequately solubilized, as the duodenum and upper part of the small intestine are bypassed
The key for patients: access compounded semaglutide only through a licensed clinical provider who can write a valid individualized prescription and who sources from a verified, FDA-registered 503B facility or a compliant 503A pharmacy
This distinction is clinically important: compounded medications undergo rigorous pharmaceutical oversight but are prepared specifically for individual patients rather than mass-manufactured batches
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