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The SUSTAIN trials assessed final once-weekly doses of 1.0 mg only, or 0.5 mg and 1.0 mg, of subcutaneous semaglutide ( Once-weekly subcutaneous semaglutide was compared with placebo ( Across the SUSTAIN program, the primary and confirmatory secondary endpoints for most trials were change from baseline in HbA 1c and body weight, respectively, to the end of treatment (30, 40, 52, or 56 weeks) ( 1c and body weight, respectively ( 1c Set al
This is not guaranteed, but for patients unable to tolerate tirzepatide, mazdutide represents an alternative worth trying once available