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Physiological stimuli such as shear stress or G protein-coupled receptor (GPCR) agonists like bradykinin promote Ca 2+ entry, leading to dissociation of the Cav-1-eNOS complex and allowing eNOS to be activated via phosphorylation by kinases such as Akt (Feron et al., 1998)
Glutathione is one of the most important antioxidants that has shown promise for brain health
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