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Interestingly, the neural circuits responsible for the metabolic effects of GLP-1R agonism may be distinct from those mediating nausea or malaise (Huang et al., 2024), suggesting that future therapies could be tailored to preserve metabolic benefits while minimizing gastrointestinal side effects
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Zepbound is manufactured under strict FDA standards Zepbound is manufactured in FDA-registered Eli Lilly facilities that adhere to current Good Manufacturing Practice (cGMP) standards
If nausea is severe, persistent, or accompanied by vomiting that prevents you from eating or staying hydrated, contact your provider immediately for dose adjustment
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