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The mechanism behind systemic effects likely involves the immune-modulating properties of GHK-Cu

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Down regulations to metabolic activity, especially in multiple down regulatory events, severely impact conversion of folate and other essential metabolites and nutrients that are paramount to the natural cycles in the body

Chemically, this is definitely not true, as the two forms are almost the same, both are polymers and the subunits can be repeated in both forms as much as you like