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Some preliminary research suggests berberine may indirectly influence GLP-1 levels or signalling, but there is no robust evidence establishing berberine as a GLP-1 receptor agonist in the manner of prescription medications
The Precision Peptide Genetic Test analyzes 14 pathways, 49 peptides, and 150+ genetic insights including variants in FTO and MC4R, and TCF7L2 that may shape baseline GLP-1, appetite-regulation, and energy-balance biology
doi:10.1046/j.1365-201x.1996.42256000.x
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