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GCGR hepatic lipid mobilisation, adipose lipolysis, increased energy expenditure, and hepatic glucose output
Instead of overcoming the metabolic adaptation, higher doses frequently exacerbate side effects like nausea, fatigue, and gastrointestinal distress
Diets that are adequate in protein and fiber and emphasize overall nutrient density can help support muscle preservation and overall health during weight loss
The second shields the molecule from degradation by DPP-4 enzymes, which would otherwise break it down within minutes
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