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Stay well hydrated, as dehydration is the fastest path to constipation on these medications
Regular moderate exercise can boost glutathione production and enzyme activity, though overtraining may deplete it
The data: Most patients who got prescribed a GLP-1 for the first time in 2023 or 2024 ended up discontinuing treatment before long, and many never filled their prescription at all, according to a November 2025 IQVIA analysis of GLP-1 prescription claims
Gastrointestinal effects are the most common
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