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For paid subscribers: The manufacturing scrutiny surrounding Novos Catalent facility adds a deeper and more complex layer to this story

Simultaneous determination of albumin and low-molecular-mass thiols in plasma by HPLC with UV detection

This difference is likely to be related to the more tightly packed ECD interface of RAMP2 and CTR, driven by the interactions with P37 Cagri , and the preferential CTR engagement by Cagri via a bypass conformation, as discussed below in the context of CTR complexes