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Epitalon: Synthetic tetrapeptide (Ala-Glu-Asp-Gly) that activates telomerase via hTERT gene upregulation

For perfusion of the colon, a catheter was inserted into the abdominal aorta, which was ligated proximally to the superior mesenteric artery, tributaries to the small intestine were ligated and the colon was vascularly perfused at a constant flow rate of 3 ml/min

The investigators compared people who had used these drugs with clinically similar patients who had not received them, then assessed whether either group was more or less likely to develop substance use disorders