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Neuroglial changes in physiological brain ageing are relatively subtle, with white matter being the most affected: in healthy old age, white matter volume is decreased by ~ 10%, whereas the grey matter is reduced by a mere 3%
It has favorable in-vitro permeability (Caco-2 and PAMPA), which predicts that oral absorption is plausible
M1 macrophages are pro-inflammatory, useful in the very early stages of healing for clearing debris but destructive if they persist
The peptide comes in lyophilized (freeze-dried) powder form and needs to be reconstituted with bacteriostatic water before use
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