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5.2 Challenges and progress in clinical research Although novel therapies such as ferroptosis inhibitors and mitochondrial protectants have shown promising efficacy in preclinical studies (164, 166, 188), their clinical translation still faces numerous challenges

Occurred in patients who received tirzepatide injection at least 2% more often than in those who received placebo (that is, with a drug-placebo difference of 2% or more)

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