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Both albiglutide and dulaglutide received FDA approval for the treatment of T2DM in 2014, with dulaglutide having an additional indication since 2020 to reduce the risk of major adverse cardiovascular events (MACE) in adults with T2DM and established cardiovascular disease or multiple cardiovascular risk factors [ Table 2 ]
A Smarter GLP-1 Dose Adjustment Program GLP-1 therapy is powerful, but its success depends on how its used
Patients with Pre-Existing Conditions Patients with certain medical conditions, such as a history of pancreatitis, thyroid disorders, or significant kidney impairment, may not be suitable candidates for these medications
Metformin itself can affect kidney function and fluid balance, though its urinary effects are modest compared to SGLT2 inhibitors or diuretics
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