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We previously found that fusion of a peptide or a single-chain variable fragment to the C-terminal end of albumin reduced FcRn binding up to 2-fold, and to a greater extent than when fused to the N-terminal end 12
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Broad Gene-Expression Signal (experimental): Reported studies show changes in gene sets tied to ECM remodeling, antioxidant defenses, inflammatory signaling, and nervous-system pathways
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