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The early evidence A small study of 27 people with obesity and PCOS who took a low dose of semaglutide found that after six months, most participants had lost weight and had more regular periods, suggesting their PCOS was under better control
Regarding use in patients with kidney disease, neither semaglutide nor tirzepatide requires dose adjustment based on renal function, even in severe CKD or end-stage renal disease
It stimulates protein synthesis and fat metabolism by binding IGF1 receptors, aiding muscle growth, recovery, and possibly skin repair
Consensus report: definition and interpretation of remission in type 2 diabetes
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