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Elevated [Ca 2+ ] i in rat GCs may be a result of exendin-4-induced PKA activation, because our experiments demonstrated that exendin-4 no longer caused changes in [Ca 2+ ] i when PKA activity was blocked by H-89 (Fig
However, the outcomes remain controversial
Developed by the American company Eli Lilly, Tirzepatide is a dual agonist for both the glucose-dependent insulinotropic polypeptide (GIP) receptor and the GLP-1 receptor
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