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This is thought to be because these medications impact the brain's hypothalamus, which is basically the brain's control center because it regulates mood, hunger, thirst and body temperature
This is a reasonable hypothesis
The primary mechanism through which GLP-1RAs induce weight loss is appetite suppression and delayed gastric emptying, mediated via hypothalamic and brainstem pathways [27]
Sep 2011;100(9):3594-601
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